Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant immune programming in neutrophils in cystic fibrosis.

Journal of leukocyte biology - 23 Feb 2024

Hu Yawen, Bojanowski Christine M, Britto Clemente J, Wellems Dianne, Song Kejing, Scull Callie, Jennings Scott, Li Jianxiong, Kolls Jay K, Wang Guoshun

Abstract excerpt

Cystic fibrosis is a life-shortening genetic disorder, caused by mutations in the gene that encodes cystic fibrosis transmembrane-conductance regulator, a cAMP-activated chloride and bicarbonate channel. Persistent neutrophilic inflammation is a major contributor to cystic fibrosis lung disease. However, how cystic fibrosis transmembrane-conductance regulator loss of function leads to excessive inflammation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cystic Fibrosis
Share to Cystic Fibrosis Research Advances

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cystic Fibrosis Transmembrane Conductance Regulator

Share to Immune responses and vaccinations

Share to Immunity

Share to Inflammation

Share to Mutation

Share to Neutrophils

Source

Identifiers

PMID: 37939820
DOI: 10.1093/jleuko/qiad139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant immune programming in neutrophils in cystic fibrosis.PMID 37939820Read ↗

ABERRANT IMMUNE PROGRAMMING IN NEUTROPHILS IN CYSTIC FIBROSISSemantic proximity Read ↗

Single Cell Transcriptional Archetypes of Airway Inflammation in Cystic FibrosisSemantic proximity Read ↗

CFTR modulators exert subset-specific phenotype remodeling on circulating neutrophils in cystic fibrosis.Semantic proximity Read ↗

The Cystic Fibrosis Neutrophil: A Specialized Yet Potentially Defective CellSemantic proximity Read ↗

Neutrophils in cystic fibrosisSemantic proximity Read ↗

Frontline Science: Pathological conditioning of human neutrophils recruited to the airway milieu in cystic fibrosisSemantic proximity Read ↗

Immune Responses in Cystic FibrosisSemantic proximity Read ↗

<i>CFTR</i>-mediated monocyte-macrophage dysfunction revealed by cystic fibrosis proband- parent comparisonsSemantic proximity Read ↗

The Challenges of Detecting Neutrophil CFTR.Semantic proximity Read ↗

Epigenetic and transcriptional plasticity drive inflammation in Cystic FibrosisSemantic proximity Read ↗

Neutrophilic inflammation as a major determinant in the progression of cystic fibrosis.Semantic proximity Read ↗

Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.