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Glioblastoma multiforme: a multi-omics analysis of driver genes and tumour heterogeneity

11 Jun 2021

Abstract excerpt

Abstract Glioblastoma (GBM) is the most aggressive and common brain cancer in adults with the lowest life expectancy. The current neuro-oncology practice has incorporated genes involved in key molecular events that drive GBM tumorigenesis as biomarkers to guide diagnosis and design treatment. This study summarizes findings describing the significant heterogeneity of GBM at the transcriptional and genomic levels,...

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PMID: 34123356
DOI: 10.1098/rsfs.2020.0072

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