Article
Molecular profiling of CNS tumors for the treatment and management of disease.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Jan 2020
Nie Qian, Hsiao Meng-Chang, Chandok Harshpreet, Rowe Shannon, Prego Matthew, Meyers Bridgette, Omerza Gregory, Hesse Andrew, Uvalic Jasmina, Soucy Melissa, Bergeron Daniel, Peracchio Michael, Burns Shelbi, Kelly Kevin, Rueter Jens, Reddi Honey V
Abstract excerpt
The World Health Organization (WHO) has defined more than 130 distinct central nervous system (CNS) tumor entities, of which glioblastoma is the most fatal primary brain tumor. However, the correlation of the molecular signatures of glioblastoma with clinical significance for precision medicine is not well-known. How, and to what extent these variants may affect clinical decision making remains uncertain. Here,...
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