Article

Integrative Multi-Omics Profiling and Machine Learning Identify Key Molecular Determinants Distinguishing Glioblastoma from Lower-Grade Glioma

2026-01-05

Abstract excerpt

<title>Abstract</title> <p>Background: Glioblastoma (GBM) and lower-grade glioma (LGG) are distinct glioma subtypes with divergent molecular landscapes and clinical outcomes. Accurate molecular characterization is critical for prognostic assessment and therapeutic decision-making. <h4>Methods:</h4> We performed an integrative multi-omics analysis combining RNA-sequencing, copy number variation (CNV), and somatic...

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Literature Corpus work: c8b5596d-3548-535e-9a31-c58c6360f6f8
DOI: 10.21203/rs.3.rs-8516036/v1

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