Article

A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress

2017-03-02

Abstract excerpt

Repetitive sequences derived from transposons make up a large fraction of eukaryotic genomes and must be silenced to protect genome integrity. Repetitive elements are often found in heterochromatin; however, the roles and interactions of heterochromatin proteins in repeat regulation are poorly understood. Here we show that a diverse set of C. elegans heterochromatin proteins act together with the piRNA and nuclea...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ab28b902-0c7c-5408-905a-b6ac5a20162f
DOI: 10.1101/112847

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stressDOI 10.1101/112847Read

The RNA Polymerase II core subunit RPB-9 directs transcriptional elongation at piRNA loci in <i>Caenorhabditis elegans</i>Semantic proximity Read

The novel HP1a interactor Clump/CG30403 safeguards transposon silencing and reproductive resilience in the <i>Drosophila</i> ovarySemantic proximity Read

Small-RNA-mediated transgenerational silencing of histone genes impairs fertility in piRNA mutants.Semantic proximity Read

The USTC complex co-opts an ancient machinery to drive piRNA transcription in <i>C. elegans</i>Semantic proximity Read

LSM2-8 and XRN-2 contribute to the silencing of H3K27me3-marked genes through targeted RNA decaySemantic proximity Read

AMX-1 is necessary for proper fertility and lack of its expression induced sterility in a p53/CEP-1 dependent manner by modulating piwi expression in C. elegansSemantic proximity Read

A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory.Semantic proximity Read

A major epigenetic programming mechanism guided by piRNAs.Semantic proximity Read

The Upstream Sequence Transcription Complex Dictates Nucleosome Positioning and Promoter Accessibility at piRNA Genes in the <i>C. elegans</i> Germ LineSemantic proximity Read

PRDE-1 is a nuclear factor essential for the biogenesis of Ruby motif-dependent piRNAs in C. elegans.Semantic proximity Read

piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in <i>D. melanogaster</i> male germlineSemantic proximity Read

A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memorySemantic proximity Read