Article

A Pan-Cancer Single-Cell Compendium of Intratumoural Heterogeneity

2026-01-07

Abstract excerpt

Intratumoural heterogeneity remains one of the most formidable challenges in oncology, driving treatment resistance, disease progression, and poor patient outcomes. To uncover the cellular programs that define tumour composition and diversity, we interrogated over 3.6 million single cells derived from more than 1,000 primary and metastatic tumours spanning 14 diverse cancer types. Through the identification and qu...

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Literature Corpus work: ab059c0e-512c-531a-a896-d6b461854017
DOI: 10.64898/2026.01.06.693992

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