Article

Deciphering Human Tumor Biology by Single-Cell Expression Profiling

2018-11-16

Abstract excerpt

Human tumors are complex ecosystems where diverse cancer and noncancer cells interact to determine tumor biology and response to therapies. Genomic and transcriptomic methods have traditionally profiled these intricate ecosystems as bulk samples, thereby masking individual cellular programs and the variability among them. Recent advances in single-cell profiling have paved the way for studying tumors at the resolu...

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Literature Corpus work: d57058f5-60e2-5f44-85dd-245e08073b27
DOI: 10.1146/annurev-cancerbio-030518-055609

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