Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genes

Abstract excerpt

BACKGROUND: To understand the roles they play in complex diseases, genes need to be investigated in the networks they are involved in. Integration of gene expression and network data is a promising approach to prioritize disease-associated genes. Some methods have been developed in this field, but the problem is still far from being solved. RESULTS: In this paper, we developed a method, Networked Gene Prioritizer...

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