Article

DSCN: double-target selection guided by CRISPR screening and network

2021-09-06

Abstract excerpt

Cancer is a complex disease with usually multiple disease mechanisms. Target combination is a better strategy than a single target in developing cancer therapies. However, target combinations are generally more difficult to be predicted. C urrent CRISPR-cas9 technology enables genome-wide screening for potential targets, but only a handful of genes have been screend as target combinations. Thus, an effective comp...

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Literature Corpus work: aad6db47-4e31-5b9d-a0c0-24a3e205f63c
DOI: 10.1101/2021.09.06.459081

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