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Validating the Target Functions and Synergistic Multi-Target, Multi-Pathway Action Mode of Compound Kushen Injection Using CRISPR/CAS

2024-05-06

Abstract excerpt

<h4>Background and Purpose</h4> Due to the complexity of traditional Chinese medicine based on complex mixtures of natural products and their multi-target mechanism of action, the discovery and validation of relevant targets have always been challenging. In previous studies, using transcriptomic methods and Compound Kushen Injection (CKI) as a model drug, we identified multiple pathways and target genes through w...

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Literature Corpus work
5f958dc1-38e7-5efc-8a2d-c009ce6376e5
DOI
10.1101/2024.05.03.592304
Open publication

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