Article

Comprehensive Glycosylation Characterization of Recombinant Human Erythropoietin by Electron-Activated Dissociation Mass Spectrometry

2024-02-21

Abstract excerpt

Recombinant human erythropoietin (rhEPO) is a glycoprotein that acts as the main hormone involved in regulating red blood cell production to treat anemia caused by chronic kidney disease or chemotherapy, which has three N-glycosylation sites and one O-glycosylation site. It contains a variety of different glycosylation modifications, such as sialyation, O-acetylation on sialic acids, etc, which causes a big challe...

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Literature Corpus work: aad51ab7-2c5d-51a6-ae4a-2b36a0caddbf
DOI: 10.21203/rs.3.rs-3941161/v1

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