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Article

Direct quality control of glycoengineered erythropoietin variants.

Nature communications - 21 Aug 2018

Čaval Tomislav, Tian Weihua, Yang Zhang, Clausen Henrik, Heck Albert J R

Abstract excerpt

Recombinant production of glycoprotein therapeutics like erythropoietin (EPO) in mammalian CHO cells rely on the heterogeneous N-glycosylation capacity of the cell. Recently, approaches for engineering the glycosylation capacities of mammalian cells for custom designed glycoforms have been developed. With these opportunities there is an increasing need for fast, sensitive, and global analysis of the...

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Source

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Identifiers

PMID: 30131559
DOI: 10.1038/s41467-018-05536-3
PMCID: PMC6104044

Genes

EPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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