Article
Fine-tuning the N-glycosylation of recombinant human erythropoietin using Chlamydomonas reinhardtii mutants.
Plant biotechnology journal - 1 Nov 2024
Leprovost S, Plasson C, Balieu J, Walet-Balieu M-L, Lerouge P, Bardor M, Mathieu-Rivet E
Abstract excerpt
Microalgae are considered as attractive expression systems for the production of biologics. As photosynthetic unicellular organisms, they do not require costly and complex media for growing and are able to secrete proteins and perform protein glycosylation. Some biologics have been successfully produced in the green microalgae Chlamydomonas reinhardtii. However, post-translational modifications like glycosylation...
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