Comprehensive Glycoproteomic Analysis of Chinese Hamster Ovary Cells

doi:10.1021/acs.analchem.8b03520

Article

Comprehensive Glycoproteomic Analysis of Chinese Hamster Ovary Cells

20 Nov 2018

Abstract excerpt

The Chinese hamster ovary (CHO) cell line is a major expression system for the production of therapeutic proteins, the majority of which are glycoproteins, such as antibodies and erythropoietin (EPO). The characterization glycosylation profile of therapeutic proteins produced from engineered CHO cells and therapeutic functions, as well as side effects, are critical to understand the important roles of...

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