Article

Chemical proteomic approach for in-depth glycosylation profiling of plasma carcinoembryonic antigen in cancer patients

2023-09-22

Abstract excerpt

Carcinoembryonic antigen (CEA) of human plasma is a biomarker of many cancer diseases, and its N-glycosylation accounts for 60% of molecular mass. It is highly desirable to characterize its glycoforms for providing additional dimension of features to increase its performance in prognosis and diagnosis of cancers. However, to systematically characterize its site-specific glycosylation is challenging due to its low...

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Literature Corpus work: 798bc505-6084-5dbd-85be-ebb4b50e51e6
DOI: 10.1101/2023.09.22.558933

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