Article

α-Synuclein strains influence multiple system atrophy via central and peripheral mechanisms

2020-10-16

Abstract excerpt

Multiple system atrophy (MSA) is a progressive neurodegenerative disease with prominent autonomic and motor features. Different disease subtypes are distinguished by their predominant parkinsonian or cerebellar signs. The pathognomonic feature of MSA is the presence of α-synuclein (αSyn) protein deposits in glial cells of the central and peripheral nervous system. It is unclear why MSA, that invariably presents wi...

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Literature Corpus work: aad37632-b69d-522b-9f44-933edec10cd6
DOI: 10.1101/2020.10.16.342089

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