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Article

ɑ-Synuclein strains and the variable pathologies of synucleinopathies.

Journal of neurochemistry - 1 Oct 2016

Peelaerts Wouter, Baekelandt Veerle

Abstract excerpt

Several decades ago, a mysterious transmissible agent was found responsible for a group of progressive and lethal encephalopathies affecting the nervous system of both animals and humans. This infectious agent showed a strain-encoded manner of inheritance even though it lacked nucleic acids. The identification of infectious proteins resolved this apparent conundrum. Misfolded infectious protein particles, or...

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Identifiers

PMID: 26924014
DOI: 10.1111/jnc.13595

Genes

SNCA

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