Article

Genetic Polymorphisms Modifying Oxidative Stress Are Associated with Disease Activity in Rheumatoid Arthritis Patients

2009-01-01

Abstract excerpt

Reactive oxygen and nitrogen species are involved in the pathology of rheumatoid arthritis (RA). Polymorphisms in genes coding for superoxide dismutases (SOD2 and SOD3), catalase (CAT), tumor necrosis factor-alpha (TNFA) and inducible NO synthase (NOS2A) may influence RA activity. We determined SOD2 Ala-9Val, SOD3 Arg213Gly, CAT C-262T, TNFA G-308A, TNFA C-857T and NOS2A (CCTTT) n polymorphisms in 327 RA patients....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: aac34907-cdb2-5258-b21a-06ad9342faa4
DOI: 10.1155/2009/147356

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic Polymorphisms Modifying Oxidative Stress Are Associated with Disease Activity in Rheumatoid Arthritis PatientsDOI 10.1155/2009/147356Read

Genetic polymorphisms modifying oxidative stress are associated with disease activity in rheumatoid arthritis patients.Semantic proximity Read

Polymorphisms in the promoter region of iNOS predispose to rheumatoid arthritis in south Indian Tamils.Semantic proximity Read

Association of C-262 polymorphism in catalase gene with rheumatoid arthritis.Semantic proximity Read

Catalase and PPARgamma2 genotype and risk of rheumatoid arthritis in Koreans.Semantic proximity Read

NO role of NOS2A susceptibility polymorphisms in rheumatoid arthritis.Semantic proximity Read

Risk-associated single nucleotide polymorphisms of mitochondrial D-loop mediate imbalance of cytokines and redox in rheumatoid arthritis.Semantic proximity Read

Polymorphic variants of antioxidative defense enzymes and their gene-gene epistatic interactions in systemic lupus erythematode patients.Semantic proximity Read

Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease.Semantic proximity Read

Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies.Semantic proximity Read

Glutathione S-transferase, catalase, and mitochondrial superoxide dismutase gene polymorphisms modulate redox potential in systemic lupus erythematosus patients from Manaus, Amazonas, Brazil.Semantic proximity Read

Gene expression, levels and polymorphism (Ala16Val) of mitochondrial superoxide dismutase in tuberculosis patients of Rajasthan.Semantic proximity Read

Variation of genes encoding nitric oxide synthases and antioxidant enzymes as potential risks of multiple sclerosis development: a preliminary study.Semantic proximity Read