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Article

Risk-associated single nucleotide polymorphisms of mitochondrial D-loop mediate imbalance of cytokines and redox in rheumatoid arthritis.

International journal of rheumatic diseases - 1 Jan 2023

Zhang Jingnan, Zhang Jingjing, Lai Ruixue, Peng Chenxing, Guo Zhanjun, Wang Cuiju

Abstract excerpt

BACKGROUND: We have identified rheumatoid arthritis (RA) risk-associated single nucleotide polymorphisms (SNPs) in the mitochondrial displacement loop (D-loop) including the major alleles of nucleotides 195T/C, 16260C/T, and 16519C/T as well as the minor alleles of nucleotides 146T/C and 150C/T previously. OBJECTIVE: We evaluated the potential relationships of these SNPs with status for oxidative stress and...

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Share to Arthritis, Rheumatoid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

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Share to Oxidation-Reduction

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 36253082
DOI: 10.1111/1756-185X.14465

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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