Article
Catalase and PPARgamma2 genotype and risk of rheumatoid arthritis in Koreans.
Rheumatology international - 1 Mar 2006
El-Sohemy Ahmed, Cornelis Marilyn C, Park Yong-Wook, Bae Sang-Cheol
Abstract excerpt
Catalase (CAT) and peroxisome proliferator activated receptor-gamma2 (PPARgamma2) are important regulators of oxidative stress and inflammation, and may contribute to the development of rheumatoid arthritis (RA). We investigated the association between CAT and PPARgamma2 genotypes and risk and severity of RA using 474 cases and 400 controls. Genotyping for the -262C-->T polymorphism of CAT and the Pro12Ala...
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