Article

Profiling copy number alterations in cell-free tumour DNA using a single-reference

2018-03-28

Abstract excerpt

<h4>Background</h4> The accurate detection of copy number alterations from the analysis of circulating cell free tumour DNA (ctDNA) in blood is essential to realising the potential of liquid biopsies. However, currently available approaches require a large number of plasma samples from healthy individuals, sequenced using the same platform and protocols to act as a reference panel. Obtaining this reference panel...

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Literature Corpus work: aaad696d-2c13-5f6f-af58-c46edfc541f2
DOI: 10.1101/290171

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