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Bioinformatics Analysis for Circulating Cell-Free DNA in Cancer

11 Jun 2019

Abstract excerpt

Molecular analysis of cell-free DNA (cfDNA) that circulates in plasma and other body fluids represents a "liquid biopsy" approach for non-invasive cancer screening or monitoring. The rapid development of sequencing technologies has made cfDNA a promising source to study cancer development and progression. Specific genetic and epigenetic alterations have been found in plasma, serum, and urine cfDNA and could...

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PMID: 31212602
DOI: 10.3390/cancers11060805

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