Article

Decreased TREM2 expression in prefrontal cortex induces cognitive impairment and sensorimotor gating deficits in schizophrenia

2026-04-03

Abstract excerpt

<title>Abstract</title> <p>Multiple lines of evidence indicate the implication of neuroinflammatory processes in the pathophysiology of schizophrenia. Microglia are brain resident immune cells and have been implicated in schizophrenia pathogenesis as their aberrant activation is one of the leading hypotheses. However, due to the limited availability proper human cell models, the role of microglia in schizophrenia...

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Literature Corpus work: aa8319bf-3bbf-5ab5-a67d-843d5bb9bdf5
DOI: 10.21203/rs.3.rs-9239420/v1

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