Article

Computational methods for integrating microscopy with chromatin structures

2018-01-01

Abstract excerpt

The genome is more than a linear sequence of bases; its spatial organisation is a key part of its function. In humans, three billion base pairs, or approximately two metres of DNA are packaged into a nucleus a few micrometres in diameter. The genome must also be organised so that it can be replicated and partitioned into daughter cells, and so that regulatory elements are positioned to affect their targets. Until...

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Literature Corpus work: a9e86f1d-a6e5-5831-824d-7a04fcca64a3
DOI: 10.17863/cam.25059

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