Article

Ion channel model reduction using manifold boundaries

2022-03-12

Abstract excerpt

Mathematical models of voltage-gated ion channels are used in basic research, industrial and clinical settings. These models range in complexity, but typically contain numerous variables representing the proportion of channels in a given state, and parameters describing the voltage-dependent rates of transition between states. An open problem is selecting the appropriate degree of complexity and structure for an i...

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Literature Corpus work: a9be7412-ddf0-5315-af4c-745540df7fcc
DOI: 10.1101/2022.03.11.483794

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