Article
Computational biology in the study of cardiac ion channels and cell electrophysiology.
Quarterly reviews of biophysics - 1 Feb 2006
Rudy Yoram, Silva Jonathan R
Abstract excerpt
The cardiac cell is a complex biological system where various processes interact to generate electrical excitation (the action potential, AP) and contraction. During AP generation, membrane ion channels interact nonlinearly with dynamically changing ionic concentrations and varying transmembrane voltage, and are subject to regulatory processes. In recent years, a large body of knowledge has accumulated on the...
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