Article

Signatures of genetic variation in human microRNAs point to processes of positive selection related to population-specific disease risks

2021-05-25

Abstract excerpt

The occurrence of natural variation in human microRNAs has been the focus of numerous studies during the last twenty years. Most of them have been dedicated to study the role of specific mutations in diseases, like cancer, while a minor fraction seek to analyse the diversity profiles of microRNAs in the genomes of human populations. In the present study we analyse the latest human microRNA annotations in the light...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a9b3a960-7d39-5348-affc-26b9d8902c6c
DOI: 10.1101/2021.05.24.445417

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Signatures of genetic variation in human microRNAs point to processes of positive selection related to population-specific disease risksDOI 10.1101/2021.05.24.445417Read

Signatures of genetic variation in human microRNAs point to processes of positive selection and population-specific disease risks.Semantic proximity Read

Signatures of Genetic Variation in Human microRNAs Point to Processes of Positive Selection and Population-specific Disease RisksSemantic proximity Read

Functional Implications of Human-Specific Changes in Great Ape microRNAs.Semantic proximity Read

Signatures of purifying and local positive selection in human miRNAs.Semantic proximity Read

Genetic variation in microRNA networks: the implications for cancer research.Semantic proximity Read

Pervasive selection against microRNA target sites in human populationsSemantic proximity Read

The role of microRNAs in cancer susceptibility.Semantic proximity Read

MicroRNA Genetic Variation: From Population Analysis to Functional Implications of Three Allele Variants Associated with Cancer.Semantic proximity Read

Comprehensive analysis of single nucleotide polymorphisms in human microRNAs.Semantic proximity Read

Toward the blood-borne miRNome of human diseases.Semantic proximity Read

microRNAs in diseases: from candidate to modifier genes.Semantic proximity Read