Article
Genetic variation in microRNA networks: the implications for cancer research.
Nature reviews. Cancer - 1 Jun 2010
Ryan Bríd M, Robles Ana I, Harris Curtis C
Abstract excerpt
Many studies have highlighted the role that microRNAs have in physiological processes and how their deregulation can lead to cancer. More recently, it has been proposed that the presence of single nucleotide polymorphisms in microRNA genes, their processing machinery and target binding sites affects cancer risk, treatment efficacy and patient prognosis. In reviewing this new field of cancer biology, we describe...
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