Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA Genetic Variation: From Population Analysis to Functional Implications of Three Allele Variants Associated with Cancer.

Human mutation - 1 Oct 2016

Torruella-Loran Ignasi, Laayouni Hafid, Dobon Begoña, Gallego Alicia, Balcells Ingrid, Garcia-Ramallo Eva, Espinosa-Parrilla Yolanda

Abstract excerpt

Nucleotide variants in microRNA regions have been associated with disease; nevertheless, few studies still have addressed the allele-dependent effect of these changes. We studied microRNA genetic variation in human populations and found that while low-frequency variants accumulate indistinctly in microRNA regions, the mature and seed regions tend to be depleted of high-frequency variants, probably as a result of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Antigens, CD

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cadherins

Share to Gene Regulatory Networks

Share to HeLa Cells

Share to MicroRNAs

Share to Neoplasms

Share to Precision Medicine

Source

Identifiers

PMID: 27397105
DOI: 10.1002/humu.23045

Genes

CDH1
KIT
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA Genetic Variation: From Population Analysis to Functional Implications of Three Allele Variants Associated with Cancer.PMID 27397105Read ↗

Signatures of Genetic Variation in Human microRNAs Point to Processes of Positive Selection and Population-specific Disease RisksSemantic proximity Read ↗

Signatures of genetic variation in human microRNAs point to processes of positive selection and population-specific disease risks.Semantic proximity Read ↗

Signatures of genetic variation in human microRNAs point to processes of positive selection related to population-specific disease risksSemantic proximity Read ↗

Evidence for positive selection on a number of MicroRNA regulatory interactions during recent human evolution.Semantic proximity Read ↗

Pervasive selection against microRNA target sites in human populationsSemantic proximity Read ↗

Genetic variation in microRNA networks: the implications for cancer research.Semantic proximity Read ↗

MicroRNA-related sequence variations in human cancers.Semantic proximity Read ↗

Pervasive Selection against MicroRNA Target Sites in Human Populations.Semantic proximity Read ↗

Human polymorphism at microRNAs and microRNA target sites.Semantic proximity Read ↗

PopTargs: A database for studying population evolutionary genetics of human microRNA target sitesSemantic proximity Read ↗

Genetic analysis and allele-specific expression of SMAD7 3'UTR variants in human colorectal cancer reveal a novel somatic variant exhibiting allelic imbalance.Semantic proximity Read ↗

Seed sequence polymorphism rs2168518 and allele-specific target gene regulation of hsa-miR-4513.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.