Article
microRNAs in diseases: from candidate to modifier genes.
Clinical genetics - 1 Apr 2010
Bandiera S, Hatem E, Lyonnet S, Henrion-Caude A
Abstract excerpt
Until recently, the search for genetic factors predisposing or causing Mendelian diseases focused almost exclusively on protein coding sequences. As essential components of the regulatory system of gene expression, microRNAs (miRNAs) hold great promises into elucidating a number of inherited diseases. The herein review focuses on the genetic variations, whether copy number variation (CNV) or single nucleotide...
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