Article
Comprehensive analysis of single nucleotide polymorphisms in human microRNAs.
PloS one - 1 Jan 2013
Han Miao, Zheng Yun
Abstract excerpt
MicroRNAs (miRNAs) are endogenous small non-coding RNAs that repress their targets at post transcriptional level. Single Nucleotide Polymorphisms (SNPs) in miRNAs can lead to severe defects to the functions of miRNAs and might result in diseases. Although several studies have tried to identify the SNPs in human miRNA genes or only in the mature miRNAs, there are only limited endeavors to explain the distribution...
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