Article
The role of microRNAs in cancer susceptibility.
BioMed research international - 1 Jan 2013
Iuliano Rodolfo, Vismara Marco Flavio Michele, Dattilo Vincenzo, Trapasso Francesco, Baudi Francesco, Perrotti Nicola
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are germline variations interspersed in the human genome. These subtle changes of DNA sequence can influence the susceptibility to various pathologies including cancer. The functional meaning of SNPs is not always clear, being, the majority of them, localized in noncoding regions. The discovery of microRNAs, tiny noncoding RNAs able to bind the 3' untranslated region (UTR)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
