Article

Sox11 Modulates Redox Homeostasis and Chemoresistance via Tcl1a and Prdx2 Upregulation in Aggressive Mcl

2023-05-22

Abstract excerpt

<title>Abstract</title> <p>Mantle cell lymphoma (MCL) is an incurable B-cell neoplasm characterized by its aggressive behavior, short responses to conventional therapies and SOX11 overexpression. Oxidative stress is known to induce tumorigenesis and tumor progression, whereas high levels of antioxidant genes have been associated with chemoresistance in different cancers. However, the role of oxidative stress in M...

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Literature Corpus work: a99662c6-28fe-5f76-9a39-e351c4059639
DOI: 10.21203/rs.3.rs-2924125/v1

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