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Article

Prognostic significance of p53, Sox11, and Pax5 co-expression in mantle cell lymphoma.

Scientific reports - 7 Jun 2021

Jing Caixia, Zheng Yuhuan, Feng Yu, Cao Xia, Xu Caigang

Abstract excerpt

Mantle cell lymphoma (MCL) is a relatively rare subtype of non-Hodgkin's lymphoma. To identify molecular biomarkers in MCL, we performed immunohistochemistry tissue arrays using biopsies from 64 MCL patients diagnosed in West China Hospital from 2012 to 2016. TP53 mutation status in those patients was also examined by sequencing. The sequencing results showed TP53 mutations were highly heterogeneous in MCL. We...

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Share to Biomarkers, Tumor
Share to Gene Expression Regulation, Neoplastic
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphoma, Mantle-Cell

Share to PAX5 Transcription Factor

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Share to Progression-Free Survival

Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 34099776
DOI: 10.1038/s41598-021-91433-7
PMCID: PMC8185106

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