Article

Cyclic GMP-AMP synthase- Stimulator of Interferon Genes Signaling and their Agonistic / Antagonistic Values

2023-02-13

Abstract excerpt

The cytosolic PRRs and Cyclic GMP-AMP synthase (cGAS) attain the capability to detect DNA viruses like, vaccinia virus, HSV1 and HSV2, cytomegalovirus, adenoviruses, human papilloma virus etc and clear them off via IFN I regulations. PRRs can recognize the pathogen associated molecular patterns- PAMPs and self-DNA in the form of damage associated molecular patterns- DAMPs under stressed conditions, when monocytes...

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Literature Corpus work: a930c930-60f3-57c8-890c-9d374bc5a5cc
DOI: 10.32388/vdsv59

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