Article

Ca <sup>2+</sup> -mediated higher-order assembly of b <sup>0,+</sup> AT–rBAT is a key step for system b <sup>0,+</sup> biogenesis and cystinuria

2021-05-07

Abstract excerpt

Cystinuria is a genetic disorder characterized by overexcretion of dibasic amino acids and cystine, which causes recurrent kidney stones and occasionally severe kidney failure. Mutations of the two responsible proteins, rBAT and b 0,+ AT, which comprise system b 0,+ , are linked to type I and non-type I cystinuria respectively and they exhibit distinct phenotypes due to protein trafficking defects or catalytic i...

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Literature Corpus work: a9299cd9-fe48-5c74-9831-a8e7782ad385
DOI: 10.1101/2021.05.06.443019

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Ca <sup>2+</sup> -mediated higher-order assembly of b <sup>0,+</sup> AT–rBAT is a key step for system b <sup>0,+</sup> biogenesis and cystinuriaDOI 10.1101/2021.05.06.443019Read

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