Article

The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1

2024-04-11

Abstract excerpt

<h4>ABSTRACT</h4> Lineage plasticity is a recognized hallmark of cancer progression that can shape therapy outcomes. The underlying cellular and molecular mechanisms mediating lineage plasticity remain poorly understood. Here, we describe a versatile in vivo platform to identify and interrogate the molecular determinants of neuroendocrine lineage transformation at different stages of prostate cancer progression....

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Literature Corpus work: a8f12102-b3d1-5d56-aaaa-e1ab43543171
DOI: 10.1101/2024.04.09.588557

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