Article

Excess of mutational jackpot events in growing populations due to gene surfing

2016-05-16

Abstract excerpt

One of the hallmarks of spontaneous mutations in growing populations is the emergence of mutational jackpot events - large mutant clones arising from mutations that by chance occur early in the development of a cellular population so that their progenitors benefit from prolonged growth. Due to their sheer size, these jackpot events, first discovered by Luria and Delbrück [1], are thought to have momentous roles in...

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Literature Corpus work: a8dff866-7538-54bb-9d61-df8514051db1
DOI: 10.1101/053405

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