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Article

Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations.

Nature - 29 Aug 2013

Lang Gregory I, Rice Daniel P, Hickman Mark J, Sodergren Erica, Weinstock George M, Botstein David, Desai Michael M

Abstract excerpt

The dynamics of adaptation determine which mutations fix in a population, and hence how reproducible evolution will be. This is central to understanding the spectra of mutations recovered in the evolution of antibiotic resistance, the response of pathogens to immune selection, and the dynamics of cancer progression. In laboratory evolution experiments, demonstrably beneficial mutations are found repeatedly, but...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23873039
DOI: 10.1038/nature12344
PMCID: PMC3758440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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