Sequential mutations in exponentially growing populations.

Abstract excerpt

Stochastic models of sequential mutation acquisition are widely used to quantify cancer and bacterial evolution. Across manifold scenarios, recurrent research questions are: how many cells are there with n alterations, and how long will it take for these cells to appear. For exponentially growing populations, these questions have been tackled only in special cases so far. Here, within a multitype branching...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteria
• Share to Models, Genetic
• Share to Mutation