Article

Immune landscape of a genetically-engineered murine model of glioma relative to human glioma by single-cell sequencing

2020-05-13

Abstract excerpt

<h4>SUMMARY</h4> <h4>Background</h4> This study focuses on the evaluation of intratumoral immune infiltrates of the Qk/trp53/Pten (QPP) triple-knockout mouse model of glioblastoma with the purpose of establishing its relevance compared to the human disease. This included an analysis at the single cell level, of immune cells composition in both spontaneous and implanted mouse tumors and of samples obtained from...

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Literature Corpus work: a8c2d877-105a-57e3-a2c1-55acc8239723
DOI: 10.1101/2020.05.11.088708

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