Article

Clonal interference and changing selective pressures shape the escape of SARS-CoV-2 from hundreds of antibodies

2025-01-24

Abstract excerpt

SARS-CoV-2 rapidly evolves to evade human immunity. While the virus's overall resistance to human polyclonal antibody responses has steadily increased over time, the dynamics by which it escaped individual monoclonal antibodies within these responses have not been thoroughly explored. Recently, a series of studies by Cao et al. used deep mutational scanning (DMS) to identify which mutations allow the Wuhan-Hu-1 re...

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Literature Corpus work: a86e02d9-513e-59b0-9b0b-5efd94e50d59
DOI: 10.1101/2025.01.22.634135

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