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Article

An antibody-escape estimator for mutations to the SARS-CoV-2 receptor-binding domain

1 Jan 2022

Abstract excerpt

A key goal of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surveillance is to rapidly identify viral variants with mutations that reduce neutralization by polyclonal antibodies elicited by vaccination or infection. Unfortunately, direct experimental characterization of new viral variants lags their sequence-based identification. Here we help address this challenge by aggregating deep mutational...

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PMID: 35573973
DOI: 10.1093/ve/veac021

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