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Article

Reduced expression of PER2 protein contrbutes to β <sub>1</sub> -AA induced cardiac autophagy rhythm disorder

2024-12-07

Abstract excerpt

It has been confirmed that heart failure may be linked to fluctuations in autophagy rhythm of cardiomyocytes throughout the day. It is known that circadian rhythms depend on the regulation of core biological clock proteins, with PER2 playing a crucial role. Our previous research has confirmed the presence of β 1 -Adrenergic receptor autoantibodies (β 1 -AA) could induce inhibition of myocardial autophagy, leadin...

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Literature Corpus work
a83750a0-377d-57aa-9107-bcb617a2be34
DOI
10.1101/2024.12.06.627296
Open publication

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Reduced expression of PER2 protein contrbutes to β <sub>1</sub> -AA induced cardiac autophagy rhythm disorderDOI 10.1101/2024.12.06.627296
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