Article

Activin Signaling Regulates Autophagy and Cardiac Aging through mTORC2

2017-05-31

Abstract excerpt

Age-dependent loss of cardiac tissue homeostasis largely impacts heart performance and contributes significantly to cardiovascular diseases later in life. Cellular quality control machinery, such as autophagy/lysosome system, plays a crucial role in maintaining cardiac health and preventing age-induced cardiomyopathy and heart failure. However, how aging alters the autophagy/lysosome system to impact cardiac funct...

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Literature Corpus work: c5802e7d-7d22-5a46-be89-7c8a5e25e62f
DOI: 10.1101/139360

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