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Role of Autophagy in Proteostasis: Friend and Foe in Cardiac Diseases

19 Dec 2018

Abstract excerpt

Due to ageing of the population, the incidence of cardiovascular diseases will increase in the coming years, constituting a substantial burden on health care systems. In particular, atrial fibrillation (AF) is approaching epidemic proportions. It has been identified that the derailment of proteostasis, which is characterized by the loss of homeostasis in protein biosynthesis, folding, trafficking, and clearance...

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PMID: 30572675
DOI: 10.3390/cells7120279

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