Article

SNX3 aggravates pathological cardiac hypertrophy via targeting ATG5-dependent autophagy

2022-10-28

Abstract excerpt

<title>Abstract</title><p>Autophagy is an intracellular lysosomal degradation pathway that plays a critical role in maintaining cardiac homeostasis. Disordered autophagy is closely related to the pathological process of many heart diseases, including cardiac hypertrophy. However, mechanisms regulating cardiac autophagy remained unclear. Previously, we found that overexpression of SNX3 induces cardiac hypertrophy i...

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Literature Corpus work: 97635c43-3be0-5dcb-aa32-c1aca27a0892
DOI: 10.21203/rs.3.rs-2169603/v1

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