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The Link between Circadian Clock Genes and Autophagy in Chronic Obstructive Pulmonary Disease

1 Jan 2021

Abstract excerpt

Chronic obstructive pulmonary disease (COPD), a progressive respiratory disease, is characterized by the alveolar epithelium injury and persistent airway inflammation. It is documented that oscillation and dysregulated expression of circadian clock genes, like Bmal1, Per1, and Per2, involved in COPD pathogenies, including chronic inflammation and imbalanced autophagy level, and targeting the associations of...

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PMID: 34733115
DOI: 10.1155/2021/2689600

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