Article
Roles of HDAC3-Orchestrated Circadian Clock Gene Oscillations in Diabetic Rats Following Myocardial Ischemia/Reperfusion Injury
2020-04-22
Abstract excerpt
<h4>Background: </h4> Circadian clock has been closely related to the development of diabetes mellitus and cardiovascular disease; the disruption of circadian clock exacerbates myocardial ischemia/reperfusion injury (MI/RI). HDAC3 is a key component of the circadian negative feedback loop by recruitmenting the expression pattern of circadian nuclear receptor Rev-erbα, then to maintain the stability of circadian ge...
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Identifiers and source
- Literature Corpus work
- f8f56232-e6de-5ce6-a6d0-d4de4415b72a
- DOI
- 10.21203/rs.3.rs-20879/v1