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Anti-obesity compounds, Semaglutide and LiPR, do not change the proportion of human and mouse POMC+ neurons

2024-12-11

Abstract excerpt

Anti-obesity medications (AOMs) have become one of the most prescribed drugs in human medicine. While AOMs are known to impact adult neurogenesis in the hypothalamus, their effects on the functional maturation of hypothalamic neurons remain unexplored. Given that AOMs target neurons in the Medial Basal Hypothalamus (MBH), which play a crucial role in regulating energy homeostasis, we hypothesized that AOMs might i...

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Literature Corpus work
a80c73b4-6ff5-5735-9b6c-4fa76189693c
DOI
10.1101/2024.12.06.627140
Open publication

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Anti-obesity compounds, Semaglutide and LiPR, do not change the proportion of human and mouse POMC+ neuronsDOI 10.1101/2024.12.06.627140
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